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PHARMACOLOGY                                                                      02 | Ambiente, Saúde e Segurança no Trabalho
                                                                                           02 | Environment, Health and Safety at Work
         Requirements
         Knowledge on Chemistry and Pharmaceutics







          To know the main administration methods and pharmaceutical forms used in each method are some of the skills a pharmacist shall have in
          order to efficiently perform his/her duties.






                                                            CONTENTS
             OBJECTIVES
                                                            Module 1 - Pharmacology       - Kinetics of Metabolism
             At the end of this training course, trainees will have acquired   - Notions on Pharmacology  - Drug Excretion
             knowledge of pharmacology, especially in what concerns   - Nature of Drugs   - Drug Half-Life
             administration of drugs, interactions and side effects.  - Relations Between   - Therapeutic Index
                                                             Pharmacokinetics and         - Effect of Drugs in Biological
                                                             Pharmacodynamics             Systems
             ADDRESSEES                                      - Stages of Therapeutic Response   - Specificity of Drugs
             Healthcare professionals and everyone interested on this   - Bioavailability  - Properties of Receptors
             subject.                                        - Clinical Pharmacology      - Drug - Receptors Interaction
                                                             - Bioavailability and Bioequivalence   - Dose - Response Curve
                                                             Assessment                   - Signal Transduction Mechanisms
                                                             - General Notions on Toxicology    in G Protein-Coupled Receptors
                                                             - Fields of Toxicology       - Adenylate Cyclase-cAMP System
                                                             - Toxic Agent, Toxicity and   - Phospholipase c/inositol
                                                             Intoxication                 Phosphate System
                                                                                          - Desensitization of G Protein-
                                                            Module 2 - Difference between   coupled Receptors
                                                            Adverse and Non-Adverse Effects
                                                            and Safety                  Module 4 - Classification and
                                                             - Drug Administration Routes and   Mechanisms of Drug Interactions
                                                             Systems                      - Physical and Chemical Interactions
                                                             - Sublingual Route           - Drug Interactions Involving Drug
                                                             - Rectal Administration      Absorption
                                                             - Parenthetic Administration    - Mechanism of Drug Interactions in
                                                             - Intravenous Route          Absorption
             INFORMATION                                     - Subcutaneous Route         - Drug Interactions Involving Drug
             Hours: 60h                                      - Intramuscular Injection    Distribution
             Time: See Training Plan                         - Intrathecal Route          - Drug Interactions Involving Drug
             Material Delivered: Training Support Material   - Epidural Anaesthesia       Metabolism
             Training: Attendance Required                   - Intraperitoneal Route      - Drug Interactions Involving Drug
             Regime: Working Hours / Post-Working Hours      - Pulmonary Absorption       Excretion
                                                             - Topical Application        - Food, Drugs and Correspondent
                                                             - Pharmacokinetics           Interactions
                                                             - Drug Absorption            - Alcohol Interactions with Other
                                                             - Biological Membranes       Drugs
             METHODOLOGIES                                                                - Alcohol Metabolism
                                                            Module 3 - Drug Binding to Plasma
             Methodologies used by the trainer will be      Proteins                      - Pharmacokinetics Interactions
                                                                                          - Pharmacodynamic Interactions
             expository, demonstrative and/or active, favouring   - Drugs that Compete for Plasma
             the latter whenever possible.                   Protein Binding
                                                             - Apparent Volume of Distribution
                                                             (Vd)
                                                             - Metabolisation or
                                                             Biotransformation of Drugs
                                                             - Reactions of Metabolism









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